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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SF3B3
All Species:
48.79
Human Site:
Y577
Identified Species:
71.56
UniProt:
Q15393
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15393
NP_036558.3
1217
135577
Y577
P
S
G
Q
L
N
E
Y
T
E
R
K
E
M
S
Chimpanzee
Pan troglodytes
XP_511081
1283
142840
Y643
P
S
G
Q
L
N
E
Y
T
E
R
K
E
M
S
Rhesus Macaque
Macaca mulatta
XP_001107025
1199
133593
Y559
P
S
G
Q
L
N
E
Y
T
E
R
K
E
M
S
Dog
Lupus familis
XP_536791
1217
135545
Y577
P
S
G
Q
L
N
E
Y
T
E
R
K
E
M
S
Cat
Felis silvestris
Mouse
Mus musculus
Q921M3
1217
135532
Y577
P
S
G
Q
L
N
E
Y
T
E
R
K
E
M
S
Rat
Rattus norvegicus
XP_001077410
1216
135436
Y576
P
S
G
Q
L
N
E
Y
T
E
R
K
E
M
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506454
1217
135474
Y577
P
S
G
Q
L
N
E
Y
T
E
R
K
E
M
S
Chicken
Gallus gallus
XP_001232348
1218
135585
Y577
P
S
G
Q
L
N
E
Y
T
E
R
K
E
M
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1LVE8
1217
135603
Y577
P
S
G
Q
L
N
E
Y
T
E
R
K
E
M
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_728546
1227
136598
Y577
P
T
G
E
L
N
E
Y
T
E
R
S
E
M
P
Honey Bee
Apis mellifera
XP_623333
1217
135272
Y577
P
T
G
Q
L
N
E
Y
T
E
R
K
K
M
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188711
1141
126889
D547
V
I
S
L
D
Q
S
D
C
L
Q
P
L
S
M
Poplar Tree
Populus trichocarpa
XP_002312063
1213
134429
E574
D
M
T
G
Q
L
M
E
V
E
K
H
E
M
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O49552
1088
121161
G508
V
L
L
A
T
G
G
G
H
L
V
Y
L
E
I
Baker's Yeast
Sacchar. cerevisiae
Q04693
1361
153766
Y653
L
S
N
Y
E
L
V
Y
F
K
I
D
V
S
S
Red Bread Mold
Neurospora crassa
Q7RYR4
1209
134021
Y595
S
D
G
S
L
A
E
Y
D
E
K
K
E
M
S
Conservation
Percent
Protein Identity:
100
94.8
98.1
99.9
N.A.
99.9
99.5
N.A.
99.6
99
N.A.
93.4
N.A.
75.4
80.5
N.A.
76.1
Protein Similarity:
100
94.8
98.2
100
N.A.
100
99.5
N.A.
99.9
99.6
N.A.
97.9
N.A.
86.9
90.2
N.A.
85.7
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
100
N.A.
100
N.A.
73.3
80
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
N.A.
100
N.A.
86.6
93.3
N.A.
6.6
Percent
Protein Identity:
58.7
N.A.
N.A.
23.5
23
51
Protein Similarity:
76.1
N.A.
N.A.
42
41.5
69.5
P-Site Identity:
26.6
N.A.
N.A.
0
20
60
P-Site Similarity:
33.3
N.A.
N.A.
0
26.6
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
7
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
7
7
0
0
7
0
0
7
7
0
0
7
0
0
0
% D
% Glu:
0
0
0
7
7
0
75
7
0
82
0
0
75
7
0
% E
% Phe:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% F
% Gly:
0
0
75
7
0
7
7
7
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
7
0
0
7
0
0
0
% H
% Ile:
0
7
0
0
0
0
0
0
0
0
7
0
0
0
7
% I
% Lys:
0
0
0
0
0
0
0
0
0
7
13
69
7
0
0
% K
% Leu:
7
7
7
7
75
13
0
0
0
13
0
0
13
0
0
% L
% Met:
0
7
0
0
0
0
7
0
0
0
0
0
0
82
7
% M
% Asn:
0
0
7
0
0
69
0
0
0
0
0
0
0
0
0
% N
% Pro:
69
0
0
0
0
0
0
0
0
0
0
7
0
0
13
% P
% Gln:
0
0
0
63
7
7
0
0
0
0
7
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
69
0
0
0
0
% R
% Ser:
7
63
7
7
0
0
7
0
0
0
0
7
0
13
75
% S
% Thr:
0
13
7
0
7
0
0
0
69
0
0
0
0
0
0
% T
% Val:
13
0
0
0
0
0
7
0
7
0
7
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
82
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _